Novel Neural Stem Cell Harvest Technology for Treatment of Neurodegenerative Diseases and Brain Damage
Overview
Neurodegenerative diseases and brain damage are prevalent medical conditions with limited treatment options. Stem cells have shown potential in treating these conditions, but the limited availability of stem cells has hindered research and treatment progress. Novel Neural Stem Cell Harvest Technology offers a solution to this problem by directly extracting neural stem cells from the patient's brain.
Project-in-charge
Dr Kangning Ren
Associate Professor and Programme Director, Department of Chemistry
Key Features
- Magnetic-nanoparticles (MNPs) are injected into the patient's brain.
- When a magnetic field is applied, the MNPs attract the neural stem cells, which are then safely harvested.
- The harvested neural stem cells can be cultured and used in stem cell therapy or clinical research.
Technology Readiness Level
Potential Applications
- Treatment of neurodegenerative diseases such as Parkinson's and Alzheimer's diseases and brain damage caused by injury or stroke.
- Clinical research on neural stem cells.
Market Outlook & Unique Value Proposition
The market for neurodegenerative disease and brain damage treatment is growing, with an increasing demand for effective treatments. Novel Neural Stem Cell Harvest Technology offers a promising solution to these conditions, with the potential for significant growth in the stem cell therapy market.
The direct extraction of neural stem cells from the patient's brain offers a safer and more reliable source of stem cells for research and treatment. The use of MNPs for harvesting also reduces the risk of complications and side effects associated with other stem cell extraction methods. Overall, Novel Neural Stem Cell Harvest Technology has the potential to revolutionize the field of regenerative medicine and improve the lives of millions of patients suffering from neurodegenerative diseases and brain damage.
Representative Publications
Zhang S.Q., Sun P., Lin K., Chan F.H.L., Gao Q, Lau WF, Roy VAL, Zhang HQ, Lai KWC*, Huang Z.F.*, Yung K.K.L.* (2019) Extracellular Nanomatrix-Induced Self-Organization of Neural Stem Cells into Miniature Substantia Nigra-Like structures with Therapeutic Effects on Parkinsonian Rats. Advanced Science, 6, 1901822
Patents
- China Patent No. ZL 201380058694.8
- Hong Kong Patent No. HK1208249
- Macao Patent No. J/003554
- US Patent No. US 9,109,203
- European Patent No. EP 2920298